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Section for healthcare professionals and other qualified operators only. This section contains information about in vitro diagnostic medical devices and is intended exclusively for healthcare professionals and other qualified operators under the applicable rules. By proceeding, you declare that you are a healthcare professional or an equivalent qualified operator and acknowledge that these contents are not intended for the general public.

LIAISON PLEX® Bloodstream Infection Portfolio

Empower clinicians to rapidly optimize treatment and patient management

Dhiman N, Emery CL, Chow S, Ho D, Granato P, Bernier B, Farhang J. 2026. Performance of the LIAISON PLEX gram-negative blood culture assay for identifying bacterial pathogens and resistance genes in blood cultures. J Clin Microbiol64:e00018-26.
https://doi.org/10.1128/jcm.00018-26I

LIAISON PLEX® Bloodstream Infection Portfolio
Clinical need

Time is critical

Bloodstream infections demand faster answers

Clinical guidelines emphasize rapid diagnostics from positive blood cultures to speed up pathogen identification and antimicrobial resistance detection, helping clinicians optimize therapy sooner and improve outcomes through active antimicrobial stewardship.

Wolk DM, Parrott JS, Babady NE, Mochon AB, Tom R, Diel C, Dien Bard J, Harrington A, Hata DJ, Roberts AL, Boyce L, Johnson JK. 0. The American Society for Microbiology’s evidence-based laboratory medicine practice guidelines for the diagnosis of bloodstream infections using rapid tests: a systematic review and meta-analysis. Clin Microbiol Rev 0:e00137-24.
https://doi.org/10.1128/cmr.00137-24

Value of rapid molecular diagnostics

Reduced time to targeted therapy

Box MJ, Sullivan EL, Ortwine KN, et. al. Outcomes of rapid identification for gram-positive bacteremia in combination with antibiotic stewardship at a community-based hospital system. Pharmacotherapy 2015;35(3):269-76.

Walker T, Dumadag S, Lee CJ, et. al. Clinical impact after laboratory implementation of the VERIGENE gram-negative bacteria microarray for positive blood cultures. J Clin Microbiol 2016; doi: 10.1128/JCM.00376-16.

Reduced length of stay

Box MJ, Sullivan EL, Ortwine KN, et. al. Outcomes of rapid identification for gram-positive bacteremia in combination with antibiotic stewardship at a community-based hospital system. Pharmacotherapy 2015;35(3):269-76.

Walker T, Dumadag S, Lee CJ, et. al. Clinical impact after laboratory implementation of the VERIGENE gram-negative bacteria microarray for positive blood cultures. J Clin Microbiol 2016; doi: 10.1128/JCM.00376-16.

Reduced mortality rates

Walker T, Dumadag S, Lee CJ, et. al. Clinical impact after laboratory implementation of the VERIGENE gram-negative bacteria microarray for positive blood cultures. J Clin Microbiol 2016; doi: 10.1128/JCM.00376-16.

Reduced hospital costs

Box MJ, Sullivan EL, Ortwine KN, et. al. Outcomes of rapid identification for gram-positive bacteremia in combination with antibiotic stewardship at a community-based hospital system. Pharmacotherapy 2015;35(3):269-76.

Walker T, Dumadag S, Lee CJ, et. al. Clinical impact after laboratory implementation of the VERIGENE gram-negative bacteria microarray for positive blood cultures. J Clin Microbiol 2016; doi: 10.1128/JCM.00376-16.

Reduced time to ID resistance

Walker T, Dumadag S, Lee CJ, et. al. Clinical impact after laboratory implementation of the VERIGENE gram-negative bacteria microarray for positive blood cultures. J Clin Microbiol 2016; doi: 10.1128/JCM.00376-16.

The LIAISON PLEX® Bloodstream Infection Portfolio

The LIAISON PLEX® Bloodstream Infection Portfolio

The LIAISON PLEX® Bloodstream Infection Solution combines three targeted molecular assays.

  • 60 targets: 48 bacteria/yeast pathogens and 12 resistance genes.
  • Split Panel Design: Streamline workflow.
  • Flexibility to meet patient-specific needs.
  • Comprehensive pathogen and resistance gene detection.
  • Optimal chemistry: Direct detection* or PCR.

*For BCP, BCN

Designed for clinical impact

Diagnostic accuracy

Gram stain guided

Limit low probability pathogens

Clarity and confidence

Control costs

Run the panels you need

Reduce unnecessary testing

Avoid the added cost

Diagnostic workflow

Positive blood culture

A positive blood culture indicates the presence of a microorganism requiring further investigation.

Sample classification

Gram stain results help classify the microorganism and guide the diagnostic pathway.

Assay selection

The appropriate Gram-positive, Gram-negative or Yeast assay is selected based on the sample profile.

Rapid clinical insights

Pathogen identification and resistance gene detection provide clinically relevant information to support treatment optimization.

Diagnostic workflow

Bloodstream Infection Solution assays menu

LIAISON PLEX® Gram-Positive Blood Culture Assay

LIAISON PLEX® Gram-Positive Blood Culture Assay

17

Total targets

Overall sensitivity*: 98.5%1
Overall specificity*: 99.7%1

* across panel targets
1 doi: 10.1128/JCM.00235-26

Gram-Positive Bacteria
 
Resistance Genes

Bacillus spp.

Staphylococcus lugdunensis

mecA/mecC

Enterococcus faecalis

Streptococcus spp.

vanA

Enterococcus faecium

Streptococcus agalactiae

vanB

Listeria spp.  

Streptococcus anginosus group

 

Staphylococcus spp.

Streptococcus pneumoniae

 

Staphyloccocus aureus

Streptococcus pyogenes

 

Staphylococcus epidermidis

  

Ordering info

Part Name
Kit Size
Registration Status
Part Number

LIAISON PLEX® Gram-Positive Blood Culture Assay

12

IVD

20-005-305

LIAISON PLEX® Gram-Negative Blood Culture Assay

LIAISON PLEX® Gram-Negative Blood Culture Assay

27

Total targets

Overall sensitivity*: 98.6%1
Overall specificity*: 99.9%1

* across panel targets
1 doi: 10.1128/JCM.00018-26

Gram-Negative Bacteria
Resistance Genes

 Acinetobacter baumannii

Klebsiella variicola

CTX-M (blaCTX-M

Acinetobacter spp.

Morganella morganii

IMP (blaIMP)

Citrobacter spp.

Neisseria meningitidis 

KPC (blaKPC

Enterobacter spp.

Proteus spp.

NDM (blaNDM)

Enterobacteriaceae/Morganellaceae

Pseudomonas aeruginosa

OXA (blaOXA

Escherichia coli

Pseudomonas spp.

SME (blaSME)

Haemophilus influenzae

Salmonella spp.

VIM (blaVIM)

Klebsiella oxytoca

Serratia marcescens

MCR

Klebsiella pneumoniae

Stenotrophomonas maltophilia

 

Ordering info

Part Name
Kit Size
Registration Status
Part Number

LIAISON PLEX® Gram-Negative Blood Culture Assay

12

IVD

20-005-303

LIAISON PLEX® Yeast Blood Culture Assay

LIAISON PLEX® Yeast Blood Culture Assay

16

Total targets

Overall sensitivity*: 98.5%1
Overall specificity*: 99.7%1

* across panel targets
1 doi: 10.1128/JCM.00362-25

Yeast
 

Candida albicans

Candida kefyr

Candida auris

Candida krusei

Candida dubliniensis

Candida lipolytica

Candida famata

Candida lusitaniae

Candida glabrata

Candida parapsilosis

Candida guilliermondii

Candida tropicalis

Candida haemulonii/duobushaemulonii

Cryptococcus neoformans/gattii

Ordering info

Part Name
Kit Size
Registration Status
Part Number

LIAISON PLEX® Yeast Blood Culture Assay

12

IVD

20-005-306

To be used on the LIAISON PLEX® System

The LIAISON PLEX® System is a next-generation, multiplex, sample-to-answer molecular diagnostic platform. Designed to support both PCR and non-amplified assays, offering the most optimal testing approach for each patient, ensuring precise and personalized diagnostics.

LIAISON PLEX®

LIAISON PLEX®

Flexibility like never before with an easy-to-use, automated system for customizable syndromic testing.

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Sample-to-customizable answer for your respiratory testing.

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TECHNOLOGY

LIAISON PLEX® Flex™ Testing

Customize panels to patient need, report only what’s necessary, and expand results without retesting.

Appropriate testing and treatment impacts patient outcomes. At Diasorin, we are committed to improving diagnostics to support clinical decisions.

Learn more

Working together

Sepsis Alliance

Diasorin is a proud sponsor of Sepsis Alliance, a leading nonprofit patient advocacy organization.

Discover more
sepsis alliance

Resources

Diasorin document repository

Dialog

Luminex document repository

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Research publications

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More details about LIAISON PLEX® Bloodstream Infection Portfolio

Get in touch

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