LIAISON® Cytomegalovirus (CMV) Diagnostic Solution
The diagnosis of Human Cytomegalovirus infection in pregnant women is of particular importance in assessing risk of fetal damage.
The LIAISON® CMV assay panel (IgG, IgM) is a complete solution to aid clinicians in patient assessment of the CMV virus.
LIAISON® CMV IgG
LIAISON® CMV IgG is a chemiluminescent assay for the qualitative determination of IgG antibodies to CMV in human serum or plasma samples.
LIAISON® CMV IgM
LIAISON® CMV IgM is a chemiluminescent assay for the qualitative determination of IgM antibodies to CMV in human serum or plasma samples.
Background
Human Cytomegalovirus (CMV) is the most common cause of viral intrauterine infection. Fetal damage is mostly due to maternal primary infection. Intrauterine transmission of CMV is significantly reduced in immunoprotected mothers compared to primary infections contracted during pregnancy (< 2% vs 40-50%, respectively). As infections are either asymptomatic or accompanied by symptoms which are non-specific for CMV, laboratory techniques are the sole means of diagnosing acute infections. Early diagnosis of primary infection requires a highly sensitive and quantitative assay for IgG and IgM antibodies, to discriminate between chronic and recent infections.
How it works
Disease evolution
Results interpretation
IgG |
IgM |
Avidity |
Diagnosis |
|---|---|---|---|
| Negative |
Negative |
|
No infection |
| Positive |
Positive |
Low |
Possible acute infection |
| Positive |
Positive |
High |
Reactivation / past infection |
| Positive |
Negative |
|
Past infection |
Why use LIAISON® Cytomegalovirus (CMV) Diagnostic Solution
The complete solution for Cytomegalovirus serology, from detection to dating of infection and solve diagnostic ambiguities
LIAISON® CMV IgM to detect acute infections
Highly sensitive IgM assays for the early detection of infection and optimal specificity through selection of the proper cut-off.
To be used on
Designed for both specialty and routine tests, LIAISON® XL immunoassay analyzer help your laboratory handle multiple patients and tests simultaneously. LIAISON® systems are trustworthy, intuitive and deliver automated continuous operation with minimal user intervention. The result is reduced turnaround time, optimal cost management and unmatched growth potential.
LIAISON® XL
Designed for large laboratories. Combine the benefits of high throughput and high sensitivity within a powerful and fully automated system that can seamlessly connect to facilitate Total Laboratory Automation.
More details about our diagnostic solutions
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