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LIAISON® Calprotectin

The LIAISON® Calprotectin assay can be used as an aid in the diagnosis of IBD, specifically Crohn’s disease and ulcerative colitis, and as an aid in differentiation of IBD from IBS.

Indications for use


Differentiate IBS (Irritable Bowel Syndrome) from IBD (Inflammatory Bowel Disease)

Target patient

Adults and children patient with suspicion of IBD

Use area

Gastroenterology, general medicine and primary care providers

Immunoassays or the detection of Calprotectin - LIAISON® Diasorin

Differentiate IBS from IBD with a single test

Diasorin offers a complete solution for the fast, accurate and automated detection of Calprotectin: LIAISON® Q.S.E.T. Device Plus automatic extraction tubes and LIAISON® Calprotectin CLIA assay.
Calprotectin is secreted by neutrophils, which infiltrate the intestinal mucosa as part of the inflammatory response. Consequently, organic diseases of the bowel result in elevated levels of fecal calprotectin. The concentration of calprotectin in stool reflects the number of neutrophils present and provides an indicator of the severity of intestinal inflammation. The non-invasive measurement of fecal calprotectin is a useful tool as an aid in differentiating IBD from IBS.

How it works

LIAISON® Calprotectin is intended for the quantitative measurement, in human stool, of fecal calprotectin.

Easy handling of stool sample


Easy handling of stool sample

The use of the LIAISON® Q.S.E.T. Device Plus reduces the preparation steps of the extracted stool samples and allows the operator to easily handle the stool, thus saving time.


35 minutes to results

Save time and unnecessary testing by quickly identifying Calprotectin.


Non-invasive method for patient

LIAISON® Calprotectin is a chemiluminescence (CLIA) sandwich assay that uses 2 monoclonal antibodies for capture and detection of calprotectin.

Diagnostic solution for the differentiation of IBS and IBD - Diasorin

Why use LIAISON® Calprotectin

Save time, provide accurate results, and easily handle stool samples.

Reliable diagnostic solution

Safely diagnose IBD while preventing the patient from further invasive investigations.

Clear interpretation of the results

Safe and clear diagnosis, due to a Calprotectin cut off value defined with literature and clinical data of more than 200 patients.

Easy extraction of stool samples

LIAISON® Q.S.E.T. Device Plus is ready to use and improves the pre-analytical process. This tool ensures the secure and simplified handling of feces.

To be used on

Designed for both specialty and routine tests, LIAISON® XL and LIAISON® XS immunoassay analyzers help your laboratory handle multiple patients and tests simultaneously. LIAISON® systems are trustworthy, intuitive and deliver automated continuous operation with minimal user intervention. The result is reduced turnaround time, optimal cost management and unmatched growth potential.

Fully Automated LIAISON® XL System - Diasorin


Designed for large laboratories. Combine the benefits of high throughput and high sensitivity within a powerful and fully automated system that can seamlessly connect to facilitate Total Laboratory Automation. 

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Fully Automated LIAISON® XS System - Diasorin


A fully automated, easy-to-use benchtop analyzer. Maximize productivity with optimal cost management, no daily maintenance, straightforward integration, and the same capabilities as Diasorin’s high-throughput analyzers. 

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More details about our diagnostic solutions

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Login to our repository for instructions for use and user manuals, assay information, protocols and much more.


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