LIAISON® Rubella virus Diagnostic Solution
The diagnosis of congenital rubella syndrome in pregnant women has a particular importance to estimate potential risk of fetal damage.
The LIAISON® Rubella assay panel (IgG, IgM) is a complete solution to support clinicians in the patient assessment of rubella infection.
LIAISON® Rubella IgG II
LIAISON® Rubella IgG II is a chemiluminescence (CLIA) assay for the quantitative determination of specific IgG antibodies to rubella virus in human serum or plasma samples.
LIAISON® Rubella IgM
LIAISON® Rubella IgM is a chemiluminescence (CLIA) assay for the quantitative determination of specific IgM antibodies to rubella virus in human serum or plasma samples.
Background
Rubella infection, acquired in the first trimester of pregnancy, is associated with a very high risk of congenital rubella syndrome (CRS). Fetal damage is mostly due to maternal primary infection. Although incidence of CRS is significantly reduced because of successful vaccination programs, especially in developed countries, rubella continues to occur because rubella vaccination coverage is not sufficient throughout the world. As infections are either asymptomatic or accompanied by symptoms which are non-specific for rubella, laboratory techniques are the sole means of diagnosing acute infections.
How it works
Disease evolution
Results interpretation
IgG |
IgM |
Diagnosis |
|---|---|---|
| Negative |
Negative |
No infection |
| Positive |
Negative |
Past infection |
| Positive |
Positive |
Acute infection / past infection (long lasting IgM) |
Why use LIAISON® Rubella virus Diagnostic Solution
A fully automated solution with the highly specific LIAISON® Rubella IgG II test and the LIAISON® Rubella IgM test allows your laboratory to report clear and unequivocal results.
High sensitive IgG assay able to detect low IgG antibody titers
LIAISON® Rubella IgG II is a sensitive assay able to detect low IgG antibody titers present in vaccinated population reducing the number of samples to be confirmed.
High sensitivity and quantitative Rubella IgM
LIAISON® Rubella IgM is a sensitive and quantitative assay for early identification of infection in at risk pregnant women.
To be used on
Designed for both specialty and routine tests, LIAISON® XL and LIAISON® XS immunoassay analyzers help your laboratory handle multiple patients and tests simultaneously. LIAISON® systems are trustworthy, intuitive and deliver automated continuous operation with minimal user intervention. The result is reduced turnaround time, optimal cost management and unmatched growth potential.
LIAISON® XL
Designed for large laboratories. Combine the benefits of high throughput and high sensitivity within a powerful and fully automated system that can seamlessly connect to facilitate Total Laboratory Automation.
LIAISON® XS
A fully automated, easy-to-use benchtop analyzer. Maximize productivity with optimal cost management, no daily maintenance, straightforward integration, and the same capabilities as Diasorin’s high-throughput analyzers.
More details about our diagnostic solutions
Login to Dialog for additional resources
Login to our repository for instructions for use and user manuals, assay information, protocols and much more.