Skip to main content

Disclaimer

You’re about to visit the U.S. Diasorin Infection Management site (us.diasorin.com/bacterialviral), intended exclusively for audiences in the United States.
By clicking the button below you confirm that you are aware of entering the U.S site

Go to US site

If you prefer to continue browsing the international (non-U.S.) Diasorin website,
click the button below.

Go to INT Site

Pursuant to the Guidelines of the Ministry of Health dated 28/03/2013 related to health advertising concerning medical devices, in vitro diagnostic medical devices and medical-surgical devices, we hereby inform you that the information contained in this website and to which you are going to access is exclusively intended for professional operators.

Learning Library

Find all published Papers, Posters, and Abstracts

Papers, Posters, and Abstracts

Paper
Natural Variability of TRAIL, IP-10, and CRP in Healthy Adults – The “HERACLES” Study

Langedijk et al. | Cytokine

Discover more
Paper
Cost-Impact Analysis of a Novel Diagnostic Test to Assess Community-Acquired Pneumonia Etiology in the Emergency Department Setting: A Multi-Country European Study

Houshmand et al. | International Journal of Environmental Research and Public Health

Discover more
Paper
Combinatorial Host-Response Biomarker Signature (BV Score) and Its Subanalytes TRAIL, IP-10, and C-Reactive Protein in Children With Mycoplasma pneumoniae Community-Acquired Pneumonia

Papan C et al. | The Journal of Infectious Diseases

Discover more
Paper
Effect of Host-Protein Test (TRAIL/IP-10/CRP) on Antibiotic Prescription and Emergency Department or Urgent Care Center Return Visits: The JUNO Pilot Randomized Controlled Trial

Singer et al. | Academic Emergency Medicine

Discover more

Videos and Webinars

A New FDA-Cleared Blood Test
Webinar

A New FDA-Cleared Blood Test

Watch the webinar
2023 AACC Annual Scientific Meeting + Clinical Lab Expo official vendor badge
Video

MeMed BV at AACC 2023 Presentation

Watch the video
Overcoming a major challenge in the ED
Video

Overcoming a major challenge in the ED

Watch the video

FAQs

MeMed BV measures three key immune response biomarkers:

  • TRAIL (TNF-Related Apoptosis-Inducing Ligand): The first FDA-cleared biomarker that rises with viral infections and decreases in bacterial infections.
  • IP-10 (Interferon Gamma-Induced Protein 10): A chemokine involved in immune cell activation and chemotaxis. Altered expression is linked to inflammation, infection, and immune dysregulation.
  • CRP (C-Reactive Protein): A well-known acute-phase protein that rises in both bacterial and viral infections, depending on the time since symptom onset.

A machine learning–derived algorithm combines these values into a single score that helps distinguish bacterial vs. viral infections within 7 days of symptom onset.

Yes. MeMed BV has a PLA CPT code 0315U. Consult CodeMap for additional details.

  • LIAISON® MeMed BV requires a serum sample.
  • MeMed Key accepts either serum or whole blood (whole blood option is FDA-cleared in the U.S.).

In the U.S.: For patients in ED or urgent care with suspected acute bacterial or viral infections, especially those with fever and symptoms ≤7 days.

Recommended Uses:

  • Antibiotic cessation in ICU patients
  • Lower respiratory tract infections (e.g., CAP, AECOPD)
  • Neonates over 34 weeks gestation, with caution in preterms

Not Recommended For:

  • Initiation of antibiotics
  • Mortality prediction in sepsis (despite FDA clearance)

In summary:

Not recommended in the ED for diagnosis or treatment initiation. 
Best used in ICU or hospitalized patients for guiding antibiotic discontinuation.

Yes. MeMed BV can identify bacterial immune responses even in the presence of viral co-infections, providing clearer guidance for treatment decisions.

The score reflects the likelihood of bacterial vs. viral infection, not disease severity.

Yes. MeMed BV is pathogen-agnostic, analyzing the host immune response instead of targeting specific pathogens. This makes it useful even for novel or unknown infectious agents.

Get in touch