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Section for healthcare professionals and other qualified operators only. This section contains information about in vitro diagnostic medical devices and is intended exclusively for healthcare professionals and other qualified operators under the applicable rules. By proceeding, you declare that you are a healthcare professional or an equivalent qualified operator and acknowledge that these contents are not intended for the general public.

Learning Library

Find all published Papers, Posters, and Abstracts

Featured

From Diagnostic Uncertainty to Whole-System Efficiency

Sepsis and severe infections place strain on emergency departments and inpatient capacity. Overcrowding, prolonged boarding, and resource strain create downstream operational and financial pressure.

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featured

Papers, Posters, and Abstracts

Abstract
Using MeMed BV to Reduce Antibiotic Use for Low Risk CAP

Le et al. |

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Poster
Host-Protein Score (Integrating TRAIL, IP-10, CRP) Distinguishes Between Viral and Viral-Bacterial Co-Infection in Adult Patients Testing Positive for Viral Detection

Arias et al. |

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Paper
Validation of a Rapid Host-Protein Score to Discriminate Bacterial from Viral Infections in Hospitalized Febrile Pediatric Patients

Noni et al. | Children

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Paper
Host-Response Testing with MeMed BV in Community-Acquired Pneumonia: An Economic Evaluation from the UK NHS Perspective

Gregg et al. | JAC- Antimicrobial Resistance

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Paper
Implementation of a Rapid Host‑Protein Diagnostic Test for Distinguishing Bacterial and Viral Infections in Adults Presenting to Urgent Care Centers: A Pragmatic Cohort Study

Kalmovich et al. | BMC Medicine

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Videos and Webinars

FAQs

MeMed BV measures three key immune response biomarkers:

  • TRAIL (TNF-Related Apoptosis-Inducing Ligand): The first FDA-cleared biomarker that rises with viral infections and decreases in bacterial infections.
  • IP-10 (Interferon Gamma-Induced Protein 10): A chemokine involved in immune cell activation and chemotaxis. Altered expression is linked to inflammation, infection, and immune dysregulation.
  • CRP (C-Reactive Protein): A well-known acute-phase protein that rises in both bacterial and viral infections, depending on the time since symptom onset.

A machine learning–derived algorithm combines these values into a single score that helps distinguish bacterial vs. viral infections within 7 days of symptom onset.

Yes. MeMed BV has a PLA CPT code 0315U. Consult CodeMap for additional details.

  • LIAISON® MeMed BV requires a serum sample.
  • MeMed Key accepts either serum or whole blood (whole blood option is FDA-cleared in the U.S.).

In the U.S.: For patients in ED or urgent care with suspected acute bacterial or viral infections, especially those with fever and symptoms ≤7 days.

Recommended Uses:

  • Antibiotic cessation in ICU patients
  • Lower respiratory tract infections (e.g., CAP, AECOPD)
  • Neonates over 34 weeks gestation, with caution in preterms

Not Recommended For:

  • Initiation of antibiotics
  • Mortality prediction in sepsis (despite FDA clearance)

In summary:

Not recommended in the ED for diagnosis or treatment initiation. 
Best used in ICU or hospitalized patients for guiding antibiotic discontinuation.

Yes. MeMed BV can identify bacterial immune responses even in the presence of viral co-infections, providing clearer guidance for treatment decisions.

The score reflects the likelihood of bacterial vs. viral infection, not disease severity.

Yes. MeMed BV is pathogen-agnostic, analyzing the host immune response instead of targeting specific pathogens. This makes it useful even for novel or unknown infectious agents.

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